Key West 4-star Hotels

Compare rates for 4-star hotels in Key West, FL from hundreds of popular travel sites on HotelsCombined.

...and more

Learn why travellers love HotelsCombined

Compare hotel ratings collected from thousands of user reviews.

One search gives you accurate pricing on affordable hotels.

Customie your results by hotel chain, amenities, price and more.

Search for hotels as many times as you want – for free.

Refine Your Search

Guest Ratings
Amenities
Freebies
See all filters

Popular 4-star hotels in Key West

These hotels are some of our user’s favourites in Key West based on booking data. Prices were last updated on 21 April 2026.
Enter your travel dates to find the best prices.
0 Duval Street, Key West, FL, United States
Located in Old Town North of Truman, this resort provides comfortable rooms with free Wi-Fi. Close to shops and restaurants, the resort is a convenient base while in Key West.
Free Wi-Fi
8.8
Excellent
540 reviews
Location
0.6 mi from city centre
1401 Simonton Street, Key West, FL, United States
Conveniently located moments from Key West, Santa Maria Suites Resort provides comfortable accommodation in Key West. It is conveniently positioned for those wishing to visit local attractions.
9.1
Excellent
1221 reviews
Location
0.6 mi from city centre
245 Front Street, Key West, FL, United States
Sunset Keys Cottage offers comfortable 4-star accommodation in Key West. Just minutes from Key West, it offers comfortable stay in a convenient location.
Free Wi-Fi
9.0
Excellent
169 reviews
Location
0.5 mi from city centre

Travel insights for hotels in Key West

Use our HotelsCombined data-powered tips to help you find your next hotel in Key West.

What is the cheapest month to book a hotel in Key West?

The cheapest month to book a hotel in Key West is June (£175). Conversely, the most expensive month to stay in Key West is February (£406).

What is the cheapest day to stay in a hotel in Key West?

The cheapest day to stay in Key West is Tuesday (£219). On the other hand, travelers can expect to pay the most on Sunday, when the average nightly price is £426.

How much is a hotel in Key West tonight?

Users have found prices for hotels in Key West tonight starting as low as £120, rising to an average cost of £287, based on searches in the last 72 hours. Prices start from £139 for a 4-star hotel in Key West for tonight.

How much is a Key West hotel room this weekend?

In the past 72 hours, we’ve seen prices for hotels in Key West this weekend for as little as £229/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as £229/night. For a 4-star hotel in Key West, the cheapest rate recently found was £240/night for this weekend.

How far ahead should you book a hotel in Key West?

Save money by booking a hotel at least 4 days before your trip to Key West. The lowest price found when booking 4 days ahead was £188 per night.

Cheapest 4-star hotels in Key West

Discover affordable 4-star hotels in Key West that provide a quality experience without breaking the bank. 4-star hotels in Key West can be found for as little as £155 per night. Price data was last updated on 21 April 2026
These are the lowest-priced 4-star hotels our users have recently found in Key West. Prices may vary based on dates selected and hotel location.
2801 North Roosevelt Boulevard, Key West, FL, United States
1.9 mi from city centre
Free Wi-Fi
£155
Avg. per night
3420 North Roosevelt Boulevard, Key West, FL, United States
2.7 mi from city centre
Free Wi-Fi
Parking
£159
Avg. per night
3990 South Roosevelt Boulevard, Key West, FL, United States
3.1 mi from city centre
£180
Avg. per night
5950 Peninsular Avenue, Key West, FL, United States
4.6 mi from city centre
Free Wi-Fi
£190
Avg. per night
725 Truman Avenue, Key West, FL, United States
0.3 mi from city centre
Free Wi-Fi
£199
Avg. per night
2001 South Roosevelt Boulevard, Key West, FL, United States
1.8 mi from city centre
£209
Avg. per night
7001 Shrimp Road, Key West, FL, United States
3.9 mi from city centre
£209
Avg. per night
526 Angela Street, Key West, FL, United States
0.1 mi from city centre
Free Wi-Fi
£224
Avg. per night
1319 Duval Street, Key West, FL, United States
0.5 mi from city centre
Free Wi-Fi
Spa
£225
Avg. per night
2401 N. Roosevelt Blvd, Key West, Key West, FL, United States
1.5 mi from city centre
£228
Avg. per night
1 Duval Street, Key West, FL, United States
0.5 mi from city centre
Free Wi-Fi
£236
Avg. per night
200 William Street, Key West, FL, United States
0.4 mi from city centre
Free Wi-Fi
£242
Avg. per night
430 Duval Street, Key West, FL, United States
0.2 mi from city centre
Free Wi-Fi
£258
Avg. per night
601 Front Street, Key West, FL, United States
0.5 mi from city centre
£283
Avg. per night
245 Front Street, Key West, FL, United States
0.4 mi from city centre
Free Wi-Fi
£294
Avg. per night

Other star-rated hotels in Key West

Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” have the most attractive prices based on their popularity. Price data was last updated on 21 April 2026.
Not set on a 4-star hotel? We’ve got plenty of other options for you to choose from. These are the most popular and best value properties in Key West based on hotel class.
3 stars
3820 N Roosevelt Blvd, Key West, FL, United States
3841 North Roosevelt Boulevard, Key West, FL, United States
2400 North Roosevelt Boulevard, Key West, FL, United States
420 Margaret Street, Key West, FL, United States
2 stars and under
1321 Simonton Street, Key West, FL, United States
3101 North Roosevelt Boulevard, Key West, FL, United States
1320 Simonton Street, Key West, FL, United States
718 South Street, Key West, FL, United States
800 Washington Street, Key West, FL, United States

Other accommodations in Key West

Find deals on places to stay in Key West that are not hotels. These are just a few of the most popular hostels and vacation rentals in the area. Pricing information was last updated on 21 April 2026.
Looking for something less traditional for your stay? Find the perfect hostel or vacation rental for your trip in Key West.
913 Duval Street, Key West, FL, United States
0.2 mi from city centre
Free Wi-Fi
Parking
£173
Avg. per night
718 South Street, Key West, FL, United States
0.6 mi from city centre
Free Wi-Fi
Parking
£164
Avg. per night
534 Eaton Street, Key West, FL, United States
0.2 mi from city centre
Free Wi-Fi
Air conditioning
£174
Avg. per night
501 Southard Street, Key West, FL, United States
0.1 mi from city centre
Free Wi-Fi
Parking
£183
Avg. per night

Where to stay in Key West

Explore different areas within Key West to find the perfect location for your stay. Map data was last updated on 21 April 2026.
The map below shows all 4-star hotels in Key West. Zoom in to find popular attractions and click on a nearby hotel for more information about the property.

Facts about 4-star hotels in Key West

Find useful tips and insights about 4-star hotels in Key West to help you make the most of your experience. FAQs were last updated on 21 April 2026.
  • How much does a 4-star hotel in Key West cost?

    For a 4-star hotel in Key West, expect to pay around £357 per night on average, with some starting as low as £264.

  • What is the cheapest 4-star hotel in Key West?

    In Key West, La Mer Hotel and Dewey House is your go-to for affordable luxury, with rates beginning at £26 for a 4-star experience.

  • What is the best 4-star hotel in Key West?

    The best 4-star hotel in Key West is The Gardens Hotel with a 9.3 rating from our users and an average price of £391/night.

  • What month is cheapest to stay in a 4-star hotel in Key West?

    For budget-conscious travellers visiting Key West, September is the month with the lowest hotel rates for 4-star accommodations, averaging £165/night.

  • How many days in advance should I book a 4-star hotel in Key West?

    For the lowest rates on a 4-star hotel in Key West, plan to book around 15 days prior to your arrival. Our users have found rates for as low as £198/night when booking 15 days in advance.

See more FAQs

Stay elsewhere in Key West