How much does a 4-star hotel in Panama City cost?

You'll find that a 4-star hotel in Panama City typically starts at £40, with an average price closer to £42 per night.

What is the cheapest 4-star hotel in Panama City?

Hotel Roma Plaza is the cheapest 4-star hotel in Panama City, where prices start as low as £22 per night.

What is the best 4-star hotel in Panama City?

For travellers seeking the top 4-star experience in Panama City, Hotel La Compañía Casco Antiguo stands out with its 9.3 user rating and an average nightly rate of £343.

4-star Hotels in Panama City from £34

Popular 4-star hotels in Panama City

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American Trade Hotel

Plaza Herrera Casco Viejo, Panama City, Panama

Featuring free Wi-Fi and an outdoor pool, this Panama City hotel is conveniently situated moments from Marcos A. Gelabert Intl. It is conveniently located for those wishing to discover the area's attractions.

Free Wi-Fi

8.6

Excellent

769 reviews

Location

2.3 mi from city centre

£149

Panama City 4-star Hotels

Compare rates for 4-star hotels in Panama City, Panama from hundreds of popular travel sites on HotelsCombined.

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Popular 4-star hotels in Panama City

These hotels are some of our user’s favourites in Panama City based on booking data. Prices were last updated on 26 April 2026.

Travel insights for hotels in Panama City

How much do hotels in Panama City cost?

The average price of a hotel in Panama City has been around £117/night over the last 3 days. You can expect year-round prices for a 5-star hotel in Panama City to be around £157/night, a 4-star hotel at £42/night, and a 3-star at £77/night on average.

What is the cheapest month to book a hotel in Panama City?

The cheapest month to book a hotel in Panama City is June (£112). Conversely, the most expensive month to stay in Panama City is January (£205).

What is the cheapest day to stay in a hotel in Panama City?

The cheapest day to stay in Panama City is Friday (£128). On the other hand, travelers can expect to pay the most on Tuesday, when the average nightly price is £140.

How much is a hotel in Panama City tonight?

Users have found prices for hotels in Panama City tonight starting as low as £15, rising to an average cost of £107, based on searches in the last 72 hours. Prices start from £33 for a 4-star hotel in Panama City for tonight.

How much is a Panama City hotel room this weekend?

How far ahead should you book a hotel in Panama City?

Save money by booking a hotel at least 85 days before your trip to Panama City. The lowest price found when booking 85 days ahead was £11 per night.

Top-rated 4-star Panama City hotels

View deals on 4-star hotels in Panama City that have the highest user reviews. Review data was last updated on 26 April 2026.

These are some of the highest-rated 4-star hotels in Panama City based on user reviews.

Cheapest 4-star hotels in Panama City

Discover affordable 4-star hotels in Panama City that provide a quality experience without breaking the bank. 4-star hotels in Panama City can be found for as little as £34 per night. Price data was last updated on 26 April 2026

These are the lowest-priced 4-star hotels our users have recently found in Panama City. Prices may vary based on dates selected and hotel location.

Other star-rated hotels in Panama City

Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” have the most attractive prices based on their popularity. Price data was last updated on 26 April 2026.

Not set on a 4-star hotel? We’ve got plenty of other options for you to choose from. These are the most popular and best value properties in Panama City based on hotel class.

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Other accommodations in Panama City

Find deals on places to stay in Panama City that are not hotels. These are just a few of the most popular hostels and vacation rentals in the area. Pricing information was last updated on 26 April 2026.

Looking for something less traditional for your stay? Find the perfect hostel or vacation rental for your trip in Panama City.

Where to stay in Panama City

Explore different areas within Panama City to find the perfect location for your stay. Map data was last updated on 26 April 2026.

The map below shows all 4-star hotels in Panama City. Zoom in to find popular attractions and click on a nearby hotel for more information about the property.

Facts about 4-star hotels in Panama City

Find useful tips and insights about 4-star hotels in Panama City to help you make the most of your experience. FAQs were last updated on 26 April 2026.

How much does a 4-star hotel in Panama City cost?

What is the cheapest 4-star hotel in Panama City?

What is the best 4-star hotel in Panama City?

Stay elsewhere in Panama City

Consider these popular 3-star hotels in Panama City

Stay at one of these Panama City 3-star hotels that users have found on HotelsCombined.

Consider these popular 5-star hotels in Panama City

Stay at one of these Panama City 5-star hotels that users have found on HotelsCombined.

Consider alternative stays in Panama City

If you are looking for a specific type of hotel, consider these options for trips to Panama City

Explore these cities in Panama

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Popular Landmarks in Panama City

Consider seeing these other popular landmarks and sights in Panama City

Cities our users search for

Based on the last 12 months of user searches on HotelsCombined