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Hotels in Sikeston

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Travel insights for hotels in Sikeston

Use our HotelsCombined data-powered tips to help you find your next hotel in Sikeston.

What is the cheapest month to book a hotel in Sikeston?

The cheapest month to book a hotel in Sikeston is January (£63). Conversely, the most expensive month to stay in Sikeston is June (£89).

What is the cheapest day to stay in a hotel in Sikeston?

The cheapest day to stay in Sikeston is Thursday (£68). On the other hand, travelers can expect to pay the most on Monday, when the average nightly price is £79.

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Cheapest hotels in Sikeston, Missouri

Discover affordable stays in Sikeston that provide a quality experience without breaking the bank. Hotels in Sikeston can be found for as low as £44 per night. There is currently one property in Sikeston that can be booked for this price. Days Inn and Suites by Wyndham Sikeston is one of the hotels that can be booked for the lowest price in Sikeston. Price data was last updated on 15 April 2026
Currently, these are the lowest-priced hotels in Sikeston we've come across for the dates selected. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.
Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 South Interstate Drive, Sikeston, MO, United States
3.3 mi from city centre
Free Wi-Fi
£44
Avg. per night
View Deal
Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 East Malone Avenue, Sikeston, MO, United States
2.8 mi from city centre
Free Wi-Fi
Parking
£44
Avg. per night
View Deal
Motel 6 Sikeston Mo
Motel 6 Sikeston Mo

Motel 6 Sikeston Mo

110 South Interstate Drive, Sikeston, MO, United States
3.4 mi from city centre
Free Wi-Fi
Parking
£44
Avg. per night
View Deal
Travel Inn and Suites- Sikeston Miner I-55 exit-67
Travel Inn and Suites- Sikeston Miner I-55 exit-67

Travel Inn and Suites- Sikeston Miner I-55 exit-67

100 Matthews Lane, Sikeston, MO, United States
3.0 mi from city centre
Free Wi-Fi
Parking
£45
Avg. per night
View Deal
Best Western Plus Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

120 South Interstate Drive, Sikeston, MO, United States
3.3 mi from city centre
Pool
Free Wi-Fi
Parking
£59
Avg. per night
View Deal
Drury Inn & Suites Sikeston
Drury Inn & Suites Sikeston

Drury Inn & Suites Sikeston

2608 East Malone Avenue, Sikeston, MO, United States
2.8 mi from city centre
Pool
Free Wi-Fi
Parking
£63
Avg. per night
View Deal
Pear Tree Inn Sikeston
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2602 East Malone Avenue, Sikeston, MO, United States
3.0 mi from city centre
Free Wi-Fi
£63
Avg. per night
View Deal
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

109 Matthews Lane, Sikeston, MO, United States
3.0 mi from city centre
Pool
Free Wi-Fi
Parking
£65
Avg. per night
View Deal
Hampton Inn by Hilton Sikeston
Hampton Inn by Hilton Sikeston

Hampton Inn by Hilton Sikeston

1240 Commerce Drive, Sikeston, MO, United States
1.4 mi from city centre
Pool
Free Wi-Fi
Parking
£68
Avg. per night
View Deal
Holiday Inn Express & Suites Sikeston By IHG
Holiday Inn Express & Suites Sikeston By IHG

Holiday Inn Express & Suites Sikeston By IHG

115 Hospitality Drive, Sikeston, MO, United States
1.3 mi from city centre
Pool
Free Wi-Fi
Parking
£69
Avg. per night
View Deal

Other accommodations in Sikeston

Find the perfect hostel, theme hotel, or holiday rental for your stay in Sikeston. There are 13 hotels in Sikeston and price data was last updated on 15 April 2026. The average price for a stay in Sikeston is £75/night.
Travel Inn and Suites- Sikeston Miner I-55 exit-67
Travel Inn and Suites- Sikeston Miner I-55 exit-67

Travel Inn and Suites- Sikeston Miner I-55 exit-67

100 Matthews Lane, Sikeston, MO, United States
3.0 mi from city centre
Free Wi-Fi
Parking
£45
Avg. per night
View Deal
Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

109 Matthews Lane, Sikeston, MO, United States
3.0 mi from city centre
Pool
Free Wi-Fi
Parking
£65
Avg. per night
View Deal

Where to stay in Sikeston

Explore different neighbourhoods and areas within Sikeston to find the perfect location for your stay. Map data was last updated on 15 April 2026.
Utilise the map to find properties close to the Sikeston area(s) or attractions you plan on visiting. You can find more information on a particular hotel within the map by clicking on its name.

Facts about staying in Sikeston

Find useful tips and insights about staying in Sikeston to help you make the most of your experience. FAQs were last updated on 15 April 2026.

  • What are the best hotels in Sikeston?

    1,176 reviews rated Drury Inn & Suites Sikeston with an average score of 9.3/10. It may also be worth looking into the Pear Tree Inn Sikeston, which received a rating of 9.0/10 from 1,308 reviews. Travel Inn and Suites- Sikeston Miner I-55 exit-67 could also be a good option, with a score of 7.5/10 from 599 reviews.

  • What are some other cities to stay in when visiting Missouri?

    In addition to Sikeston, travellers opt to visit Kansas City when visiting Missouri. Branson is also a popular choice to visit.

  • How many hotels are there in Sikeston?

    In total, there are 13 hotels to choose from in Sikeston, compared to 14,032 properties in Missouri.

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