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Hotels in Santa Cruz, Seville

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Popular hotels in Santa Cruz, Seville

Discover well-known properties in Santa Cruz that are favoured by visitors more than others. There are 607 hotels in Santa Cruz and price data was last updated on 19 August 2025. The average price for a hotel in Santa Cruz is £179/night.
These hotels are among the most popular properties in the Santa Cruz area. Users can utilise the filters available to narrow down their search.

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Los Seises Sevilla, a Tribute Portfolio Hotel
Los Seises Sevilla, a Tribute Portfolio Hotel

Los Seises Sevilla, a Tribute Portfolio Hotel

Calle Segovias, 6, Seville, Andalusia, Spain
Providing free Wi-Fi and a rooftop pool, Los Seises Sevilla, a Tribute Portfolio Hotel is situated in Seville and is a brief walk from Plaza De San Francisco, Museo del Baile Flamenco and Centro de Interpretacion Juderia de Sevilla. It is close to Casa de la Memoria de Al-Andalus.
Free Wi-Fi
8.7
Excellent
2727 reviews
Location
0.3 mi from city centre
£119
View Deal
Hotel Boutique Casa de Colón
Hotel Boutique Casa de Colón

Hotel Boutique Casa de Colón

Hernando Colon 3, Seville, Andalusia, Spain
Hotel Casa de Colón is situated in Casco Antiguo and provides a range of premium amenities such as free Wi-Fi and a marble bathroom. It also features a ticket service, a 24-hour reception and babysitting/child services.
Free Wi-Fi
8.5
Excellent
1988 reviews
Location
0.4 mi from city centre
£75
View Deal
Hotel Doña María
Hotel Doña María

Hotel Doña María

Don Remondo 19, Seville, Andalusia, Spain
Set in Santa Cruz, Hotel Doña Maria is close to Museo del Baile Flamenco and Plaza De San Francisco, and offers free Wi-Fi, an outdoor pool and a swim-up bar. It is moments from Hospital de los Venerables and Casa de la Memoria de Al-Andalus.
Free Wi-Fi
8.8
Excellent
5525 reviews
Location
0.3 mi from city centre
£81
View Deal
Eurostars Sevilla Boutique
Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

Calle Abades 41-43, Seville, Andalusia, Spain
Providing an outdoor pool, a sauna and free Wi-Fi, Eurostars Sevilla Boutique is close to nearby attractions, such as Jardines de Murillo, Plaza De San Francisco and Alcázar. It is moments from Hospital de los Venerables, Casa de la Memoria de Al-Andalus and Museo del Baile Flamenco.
Free Wi-Fi
9.0
Excellent
2948 reviews
Location
0.2 mi from city centre
£85
View Deal
Apartamentos Murillo
Apartamentos Murillo

Apartamentos Murillo

Lope de Rueda, 16, Seville, Andalusia, Spain
Apartamentos Murillo is located in Santa Cruz and is a 10-minute walk from Museo del Baile Flamenco, Casa Lonja de Mercaderes and Alcázar. It is close to Casa de la Memoria de Al-Andalus and Hospital de los Venerables.
Free Wi-Fi
9.3
Excellent
2579 reviews
Location
0.2 mi from city centre
£79
View Deal
Hotel Casa 1800 Sevilla
Hotel Casa 1800 Sevilla

Hotel Casa 1800 Sevilla

Rodrigo Caro, 6, Seville, Andalusia, Spain
Offering free Wi-Fi and a rooftop pool, Hotel Casa 1800 Sevilla is within a short walk of Alcázar and Plaza De San Francisco. This unique property is ideally located in Santa Cruz and is within walking distance of San Bernardo.
Free Wi-Fi
9.3
Excellent
2274 reviews
Location
0.2 mi from city centre
£97
View Deal
Hotel Boutique Elvira Plaza
Hotel Boutique Elvira Plaza

Hotel Boutique Elvira Plaza

Plaza de Doña Elvira, 5, Seville, Andalusia, Spain
This 3-star hotel is found in Santa Cruz, and offers a range of premium amenities such as a marble bathroom and free Wi-Fi. It also features an express check-in and check-out feature, a bowling alley and a ticket service.
Free Wi-Fi
8.3
Excellent
965 reviews
Location
0.3 mi from city centre
£58
View Deal
Hotel Casa Del Poeta
Hotel Casa Del Poeta

Hotel Casa Del Poeta

Don Carlos Alonso Chaparro 3, Seville, Andalusia, Spain
Situated in Seville, Hotel Casa Del Poeta is an easy drive from Archaeological Ensemble of Italica and offers private parking on site. Some of the popular facilities at this unique 4-star hotel include free Wi-Fi and a marble bathroom.
Free Wi-Fi
9.5
Excellent
1577 reviews
Location
0.2 mi from city centre
£141
View Deal
Hotel Legado Alcazar
Hotel Legado Alcazar

Hotel Legado Alcazar

Calle Mariana De Pineda, 18, Seville, Andalusia, Spain
This luxury 4-star hotel provides multiple premium features, such as a coffee maker and a spa bath. This chic property is ideally situated in Santa Cruz.
Free Wi-Fi
9.2
Excellent
1381 reviews
Location
0.4 mi from city centre
£92
View Deal
U-Sense Sevilla Centro
U-Sense Sevilla Centro

U-Sense Sevilla Centro

Calle Alvarez Quintero 52, Seville, Andalusia, Spain
Situated in Casco Antiguo, this hotel is just a short walk from Alcázar, Jardines de Murillo and Centro de Interpretacion Juderia de Sevilla. A short stroll from Plaza Nueva, it offers chic rooms equipped with ironing facilities and a mini bar.
Free Wi-Fi
8.9
Excellent
1523 reviews
Location
0.3 mi from city centre
£72
View Deal
All 607 hotels in Santa Cruz

Travel insights for hotels in Santa Cruz

Use our HotelsCombined data-powered tips to help you find your next hotel in Santa Cruz.

What is the cheapest month to book a hotel in Santa Cruz?

The cheapest month to book a hotel in Santa Cruz is January (£49). Conversely, the most expensive month to stay in Santa Cruz is June (£389).

What is the cheapest day to stay in a hotel in Santa Cruz?

The cheapest day to stay in Santa Cruz is Saturday (£44). On the other hand, travelers can expect to pay the most on Monday, when the average nightly price is £236.

How much is a hotel in Santa Cruz tonight?

Users have found prices for hotels in Santa Cruz tonight starting as low as £38, rising to an average cost of £45, based on searches in the last 72 hours. Prices start from £50 for a 4-star hotel in Santa Cruz for tonight.

How much is a Santa Cruz hotel room this weekend?

In the past 72 hours, we’ve seen prices for hotels in Santa Cruz this weekend for as little as £39/night. If you’re specifically looking for a 3-star hotel this weekend, our users have found prices as low as £39/night. For a 4-star hotel in Santa Cruz, the cheapest rate recently found was £61/night for this weekend.

How far ahead should you book a hotel in Santa Cruz?

Save money by booking a hotel at least 6 days before your trip to Santa Cruz. The lowest price found when booking 6 days ahead was £33 per night.
Find deals

Top-rated Santa Cruz, Seville hotels

Browse through properties in Santa Cruz that have received the highest ratings from guests. There are currently 607 properties in Santa Cruz and data was last updated on 19 August 2025.
These Santa Cruz properties are among the highest rated by our users. Make sure to read hotel descriptions and reviews to find the right property right for you.
El Rey Moro Hotel Boutique
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

Reinoso, 8, Seville, Andalusia, Spain
0.2 mi from city centre
Free Wi-Fi
£97
Avg. per night
View Deal
Halo Boutique Hotel
Halo Boutique Hotel

Halo Boutique Hotel

Calle Gloria, 3, Seville, Andalusia, Spain
0.3 mi from city centre
Free Wi-Fi
£68
Avg. per night
View Deal
Hotel Alfonso XIII, A Luxury Collection Hotel, Seville
Hotel Alfonso XIII, A Luxury Collection Hotel, Seville

Hotel Alfonso XIII, A Luxury Collection Hotel, Seville

San Fernando 2, Seville, Andalusia, Spain
0.5 mi from city centre
Free Wi-Fi
£280
Avg. per night
View Deal
Eme Catedral Mercer Hotel
Eme Catedral Mercer Hotel

Eme Catedral Mercer Hotel

Calle Alemanes 27, Seville, Andalusia, Spain
0.3 mi from city centre
Free Wi-Fi
£144
Avg. per night
View Deal

Cheapest hotels in Santa Cruz, Seville

Discover affordable stays in Santa Cruz that provide a quality experience without breaking the bank. Hotels in Santa Cruz can be found for as low as £17 per night. There is currently one property in Santa Cruz that can be booked for this price. Toc Hostel Sevilla is one of the hotels that can be booked for the lowest price in Santa Cruz. Price data was last updated on 19 August 2025
Currently, these are the lowest-priced hotels in Santa Cruz we've come across for the dates selected. Prices can differ depending on the dates selected, so use the search form to browse more options if you have flexibility.
Toc Hostel Sevilla
Toc Hostel Sevilla

Toc Hostel Sevilla

Calle Miguel Manara,18-22, Seville, Andalusia, Spain
0.4 mi from city centre
Free Wi-Fi
£17
Avg. per night
View Deal
Onefam Catedral
Onefam Catedral

Onefam Catedral

Jamerdana 4, Seville, Andalusia, Spain
0.2 mi from city centre
Free Wi-Fi
Air conditioning
£17
Avg. per night
View Deal
Pension Vergara , Sevilla
Pension Vergara , Sevilla

Pension Vergara , Sevilla

Ximenez de Enciso, 11, Seville, Andalusia, Spain
0.2 mi from city centre
Free Wi-Fi
£21
Avg. per night
View Deal
La Puerta de Palacio - Adults Only
La Puerta de Palacio - Adults Only

La Puerta de Palacio - Adults Only

Calle Miguel Mañara, 8, Seville, Andalusia, Spain
0.4 mi from city centre
Free Wi-Fi
£38
Avg. per night
View Deal
Hotel Alcántara
Hotel Alcántara

Hotel Alcántara

Calle Ximenez De Enciso 28, Seville, Andalusia, Spain
0.1 mi from city centre
Free Wi-Fi
£40
Avg. per night
View Deal
Santacruz Hostal Plaza
Santacruz Hostal Plaza

Santacruz Hostal Plaza

Santa Teresa, 15, Seville, Andalusia, Spain
0.2 mi from city centre
Free Wi-Fi
£40
Avg. per night
View Deal
Hotel Murillo
Hotel Murillo

Hotel Murillo

Calle Lope de Rueda, 7-9, Seville, Andalusia, Spain
0.2 mi from city centre
Free Wi-Fi
£41
Avg. per night
View Deal
Hotel Convento La Gloria
Hotel Convento La Gloria

Hotel Convento La Gloria

Calle Argote de Molina, 26 - 28, Seville, Andalusia, Spain
0.3 mi from city centre
Free Wi-Fi
£46
Avg. per night
View Deal
Basic Hotel Sevilla Catedral
Basic Hotel Sevilla Catedral

Basic Hotel Sevilla Catedral

Álvarez Quintero, 38, Seville, Andalusia, Spain
0.4 mi from city centre
Free Wi-Fi
£46
Avg. per night
View Deal
Hotel Doña Lina
Hotel Doña Lina

Hotel Doña Lina

Calle Gloria 7, Seville, Andalusia, Spain
0.3 mi from city centre
Free Wi-Fi
£46
Avg. per night
View Deal
Sercotel Las Casas de los Mercaderes
Sercotel Las Casas de los Mercaderes

Sercotel Las Casas de los Mercaderes

Calle Alvarez Quintero, 9, Seville, Andalusia, Spain
0.4 mi from city centre
Free Wi-Fi
£51
Avg. per night
View Deal
Palacio Alcazar
Palacio Alcazar

Palacio Alcazar

Plaza de la Alianza, 11, Seville, Andalusia, Spain
0.3 mi from city centre
Free Wi-Fi
£51
Avg. per night
View Deal
Lukanda Mariana
Lukanda Mariana

Lukanda Mariana

Calle Mariana de Pineda, 10, Seville, Andalusia, Spain
0.4 mi from city centre
Free Wi-Fi
Airport shuttle
£54
Avg. per night
View Deal
Hotel Boutique Casas de Santa Cruz
Hotel Boutique Casas de Santa Cruz

Hotel Boutique Casas de Santa Cruz

C/ Pimienta, 4, Seville, Andalusia, Spain
0.3 mi from city centre
Free Wi-Fi
£56
Avg. per night
View Deal
Isa Sevilla Suites
Isa Sevilla Suites

Isa Sevilla Suites

Calle Angeles, 11, Seville, Andalusia, Spain
0.2 mi from city centre
Free Wi-Fi
£58
Avg. per night
View Deal

Hotel prices in Santa Cruz

Get a sense of the average price and most popular properties to stay in Santa Cruz to help you budget for your trip accordingly. Hotels that are booked the most in each class receive the “Most popular” badge. Hotels with the “Best value” badge are the most popular hotels in Santa Cruz at attractive prices. Price data was last updated on 19 August 2025.
Hotels located in the Santa Cruz area sorted by price and hotel class. Change the dates at the top of the page to see more options in Santa Cruz.
4 stars +
Hotel Alfonso XIII, A Luxury Collection Hotel, Seville
Hotel Alfonso XIII, A Luxury Collection Hotel, Seville

Hotel Alfonso XIII, A Luxury Collection Hotel, Seville

San Fernando 2, Seville, Andalusia, Spain
£280
View Deal
Eme Catedral Mercer Hotel
Eme Catedral Mercer Hotel

Eme Catedral Mercer Hotel

Calle Alemanes 27, Seville, Andalusia, Spain
£144
View Deal
Los Seises Sevilla, a Tribute Portfolio Hotel
Los Seises Sevilla, a Tribute Portfolio Hotel

Los Seises Sevilla, a Tribute Portfolio Hotel

Calle Segovias, 6, Seville, Andalusia, Spain
£119
View Deal
Hotel Doña María
Hotel Doña María

Hotel Doña María

Don Remondo 19, Seville, Andalusia, Spain
£81
View Deal
Eurostars Sevilla Boutique
Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

Calle Abades 41-43, Seville, Andalusia, Spain
£85
View Deal
3 stars
Hotel Boutique Casa de Colón
Hotel Boutique Casa de Colón

Hotel Boutique Casa de Colón

Hernando Colon 3, Seville, Andalusia, Spain
£75
View Deal
Apartamentos Murillo
Apartamentos Murillo

Apartamentos Murillo

Lope de Rueda, 16, Seville, Andalusia, Spain
£79
View Deal
Hotel Boutique Elvira Plaza
Hotel Boutique Elvira Plaza

Hotel Boutique Elvira Plaza

Plaza de Doña Elvira, 5, Seville, Andalusia, Spain
£58
View Deal
U-Sense Sevilla Centro
U-Sense Sevilla Centro

U-Sense Sevilla Centro

Calle Alvarez Quintero 52, Seville, Andalusia, Spain
£72
View Deal
Hotel Boutique Casas de Santa Cruz
Hotel Boutique Casas de Santa Cruz

Hotel Boutique Casas de Santa Cruz

C/ Pimienta, 4, Seville, Andalusia, Spain
£56
View Deal
2 stars and under
Onefam Catedral
Onefam Catedral

Onefam Catedral

Jamerdana 4, Seville, Andalusia, Spain
£17
View Deal
Hotel Murillo
Hotel Murillo

Hotel Murillo

Calle Lope de Rueda, 7-9, Seville, Andalusia, Spain
£41
View Deal
Hotel Alcántara
Hotel Alcántara

Hotel Alcántara

Calle Ximenez De Enciso 28, Seville, Andalusia, Spain
£40
View Deal
Toc Hostel Sevilla
Toc Hostel Sevilla

Toc Hostel Sevilla

Calle Miguel Manara,18-22, Seville, Andalusia, Spain
£17
View Deal
Pension Vergara , Sevilla
Pension Vergara , Sevilla

Pension Vergara , Sevilla

Ximenez de Enciso, 11, Seville, Andalusia, Spain
£21
View Deal

Where to stay in Santa Cruz

Explore different neighbourhoods and areas within Santa Cruz to find the perfect location for your stay. Map data was last updated on 19 August 2025.
Navigate to the areas in Santa Cruz you plan to visit to find hotels that are close by. You can find more information on a particular hotel within the map by clicking on its name.

Facts about staying in Santa Cruz, Seville

Find useful tips and insights about staying in Santa Cruz to help you make the most of your experience. FAQs were last updated on 19 August 2025.

  • What are the best hotels in Santa Cruz?

    Santa Cruz is home to many highly-rated hotels, one of which is Eme Catedral Mercer Hotel, which has a current rating of 8.4. For other potential stays, consider Sercotel Las Casas de los Mercaderes and Hotel Doña María, which can also be great places to stay in Santa Cruz.

  • What is a good hotel near Universidad de Sevilla?

    A good hotel close to Universidad de Sevilla is Melia Sevilla (rated 8.5/10 from 5,192 reviews).

  • What is a good hotel in Santa Cruz near Maria Luisa Park?

    Melia Sevilla is rated 8.5 from 5,192 reviews and is close to Maria Luisa Park.

  • Is there a good hotel near Hospital de los Venerables?

    If you’re visiting Hospital de los Venerables then the nearby Melia Sevilla is a popular hotel with HotelsCombined users (5,192 reviews scoring it at an average 8.5/10).

  • How much is a cheap hotel in Santa Cruz?

    HotelsCombined users have found cheap hotels in Santa Cruz starting from £38 per night in the last 3 days.

  • What are the most popular landmarks to visit in Santa Cruz?

    The most popular landmark in Santa Cruz is Universidad de Sevilla located in Seville, followed by Maria Luisa Park and Hospital de los Venerables, located in Seville and Seville, respectively. Depending on where and how long you plan on staying in Santa Cruz, you may be able to visit at least one of these cities.

See more FAQs

Find better results for your stay in Santa Cruz

Consider these popular 3-star hotels in Santa Cruz

Stay at one of these Santa Cruz 3-star hotels that users have found on HotelsCombined.
Hotel Boutique Casa de Colón
U-Sense Sevilla Centro
Hotel Boutique Elvira Plaza
Apartamentos Murillo

Search cheap hotels with HotelsCombined. Use the hotel finder to search for the cheapest hotel deal for all major destinations around the world. HotelsCombined searches hundreds of hotel booking sites to help you find hotels and book the ones that suit you best. Since HotelsCombined searches many hotel sites at once, you can find discounted hotels quickly, including Hotels Under £37 and Hotels Under £74. Discover hotel discounts now and make your hotel reservation today.